Effects of riboflavin analogues and diuretics on the spontaneously hypertensive rat heart

@article{Bhaskar2005EffectsOR,
  title={Effects of riboflavin analogues and diuretics on the spontaneously hypertensive rat heart},
  author={M. Bhaskar and D. Trachewsky and R. Stith and Y. S. Reddy},
  journal={Basic Research in Cardiology},
  year={2005},
  volume={85},
  pages={444-452}
}
SummaryThe chronic treatment of spontaneously hypertensive rats (SHR) with 7,8-dimethyl-10-(3-chlorobenzyl) isoalloxazine [CBI], 7,8-diethyl-10-aminol isoalloxazine [DEAI], enduron (methyclothiazide) and amiloride were studied for their effects on blood pressure and cardiac contractile protein ATPasc activities. After 35 weeks of treatment all the above antihypertensive agents showed a decrease in blood pressure in the SHR (p<0.01). Chronic treatment with CBI, DEAI, enduron, and amiloride… 

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