Corpus ID: 22655088

Effects of retinoic acid on the expression of a tumor rejection antigen (heat shock protein gp96) in human cervical cancer.

@article{Santin1998EffectsOR,
  title={Effects of retinoic acid on the expression of a tumor rejection antigen (heat shock protein gp96) in human cervical cancer.},
  author={Alessandro D. Santin and Paul L. Hermonat and Antonella Ravaggi and M. Chiriva-Internati and Sergio Pecorelli and Groesbeck P Parham},
  journal={European journal of gynaecological oncology},
  year={1998},
  volume={19 3},
  pages={
          229-33
        }
}
Retinoids are a class of compounds structurally related to vitamin A which have been found to be active agents experimentally as well as clinically in the prevention and treatment of cervical cancer. Recent data have suggested that in addition to their key regulatory role during epithelial cell differentiation, they could also contribute to enhanced cellular and humoral immunity against tumor cells. Hsp gp96 molecules have recently been implicated in the presentation of tumor and viral antigens… Expand
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