Effects of retinoic acid (RA) on the growth and phenotypic expression of several human neuroblastoma cell lines.

Abstract

It has been shown that retinoic acid (RA) can promote morphologic differentiation and inhibit the growth of a human neuroblastoma cell line, LA-N-1. The present study tests the histological generality of these phenomena by determining the effects of RA on seven other human neuroblastoma cell lines. Results show that RA strongly inhibited anchorage-dependent… (More)

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