Effects of resolvin D1 on inflammatory responses and oxidative stress of lipopolysaccharide-induced acute lung injury in mice.

@article{Wang2014EffectsOR,
  title={Effects of resolvin D1 on inflammatory responses and oxidative stress of lipopolysaccharide-induced acute lung injury in mice.},
  author={Lei Wang and Ruixia Yuan and Chengyue Yao and Qingping Wu and Marie Christelle and Wanli Xie and Xingcai Zhang and Wei Sun and Huiqing Wang and Shang-long Yao},
  journal={Chinese medical journal},
  year={2014},
  volume={127 5},
  pages={803-9}
}
BACKGROUND A variety of inflammatory mediators and effector cells participate together in acute lung injury, and lead to secondary injury that is due to an inflammatory cascade and secondary diffuse lung parenchyma injury. Inflammation is associated with an oxidative stress reaction, which is produced in the development of airway inflammation, and which has positive feedback on inflammation itself. Resolvin D1 can reduce the infiltration of neutrophils, regulate cytokine levels and reduce the… CONTINUE READING

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