Effects of repeated intravenous infusions of the plasticizer di-(2-ethylhexyl) phthalate in young male rats

@article{Sjberg1985EffectsOR,
  title={Effects of repeated intravenous infusions of the plasticizer di-(2-ethylhexyl) phthalate in young male rats},
  author={Per Sj{\"o}berg and Nils Gunnar Lindquist and Gunilla Montin and Leif Pl{\"o}en},
  journal={Archives of Toxicology},
  year={1985},
  volume={58},
  pages={78-83}
}
The effects of six iv infusions of an emulsion containing the plasticizer di(2-ethylhexyl) phthalate (DEHP) on the liver and testes were investigated in 40-day-old rats. Groups of five to six animals received the emulsion every other day in doses of 0, 5, 50 or 500 mg DEHP/kg body weight. Liver effects were studied by histological examination and by measuring bromsulfophthalein clearance, peroxisomal proliferation and certain enzymes in serum. Testicular effects were evaluated by light and… CONTINUE READING
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