Effects of renal tubular dysfunction on bone in tenofovir-exposed HIV-positive patients.

@article{Hamzah2015EffectsOR,
  title={Effects of renal tubular dysfunction on bone in tenofovir-exposed HIV-positive patients.},
  author={Lisa Hamzah and A. A. H. S. Samarawickrama and Lucy J. Campbell and Matthew Pope and Keith Burling and Martin Fisher and Yvonne C Gilleece and Karen E Walker-Bone and Frank A. Post},
  journal={AIDS},
  year={2015},
  volume={29 14},
  pages={1785-1792}
}
OBJECTIVES Tenofovir disoproxil fumarate (TDF) may cause renal tubular dysfunction (RTD) and reduce bone mineral density (BMD). We examined the relationship between RTD and BMD in TDF-exposed HIV-positive men. DESIGN AND METHODS We analysed urinary retinol-binding protein/creatinine ratio (RBPCR) and fractional excretion of phosphate (FEPO4) to quantify RTD in a cross-sectional sample of randomly selected HIV-positive men at a single tertiary outpatient clinic. BMD at the lumbar spine and hip… CONTINUE READING
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