Effects of ramipril on the neurohormonal response to exercise in patients with mild or moderate congestive heart failure.

@article{Sigurdsson1994EffectsOR,
  title={Effects of ramipril on the neurohormonal response to exercise in patients with mild or moderate congestive heart failure.},
  author={Axel F Sigurdsson and Karl Swedberg and Bengt Ullman},
  journal={European heart journal},
  year={1994},
  volume={15 2},
  pages={247-54}
}
Static measurements of plasma neurohormones at rest may not be adequate to detect alterations in cardiovascular control mechanisms in congestive heart failure (CHF). Therefore, it is of interest to study neurohormonal activation during different physiological conditions. Plasma neurohormones were measured in 54 patients on diuretic therapy for mild or moderate CHF. Samples were taken at rest and immediately after maximal bicycle exercise, before and after 12 weeks of treatment with ramipril or… CONTINUE READING

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Plasma angiotensin converting enzyme activity and ANP were reduced by ramipril compared to placebo , both at rest and after exercise , but levels of angiotensin II , aldosterone and nordrenaline were not significantly affected .
Plasma angiotensin converting enzyme activity and ANP were reduced by ramipril compared to placebo , both at rest and after exercise , but levels of angiotensin II , aldosterone and nordrenaline were not significantly affected .
Plasma angiotensin converting enzyme activity and ANP were reduced by ramipril compared to placebo , both at rest and after exercise , but levels of angiotensin II , aldosterone and nordrenaline were not significantly affected .
Plasma levels of angiotensin II , aldosterone , atrial natriuretic peptide ( ANP ) and noradrenaline were increased after maximal exercise compared to rest .
Plasma levels of angiotensin II , aldosterone , atrial natriuretic peptide ( ANP ) and noradrenaline were increased after maximal exercise compared to rest .
Plasma angiotensin converting enzyme activity and ANP were reduced by ramipril compared to placebo , both at rest and after exercise , but levels of angiotensin II , aldosterone and nordrenaline were not significantly affected .
Plasma angiotensin converting enzyme activity and ANP were reduced by ramipril compared to placebo , both at rest and after exercise , but levels of angiotensin II , aldosterone and nordrenaline were not significantly affected .
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