Effects of raclopride in the nucleus accumbens on ethanol seeking and consumption.

@article{Czachowski2001EffectsOR,
  title={Effects of raclopride in the nucleus accumbens on ethanol seeking and consumption.},
  author={C. Czachowski and A. Chappell and H. Samson},
  journal={Alcoholism, clinical and experimental research},
  year={2001},
  volume={25 10},
  pages={
          1431-40
        }
}
  • C. Czachowski, A. Chappell, H. Samson
  • Published 2001
  • Psychology, Medicine
  • Alcoholism, clinical and experimental research
  • BACKGROUND Nucleus accumbens dopamine has been shown to play a role in the processing of behaviorally relevant stimuli and to mediate ethanol-reinforced responding. Previous research that used a fixed-ratio schedule of responding maintained by the presentation of small dippers (0.1 ml) of ethanol demonstrated that the dopamine D2 antagonist, raclopride, decreased total responding for ethanol by both delaying the onset of responding and causing the early termination of lever-press behavior… CONTINUE READING
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    References

    SHOWING 1-10 OF 36 REFERENCES
    Alcohol self-administration: further examination of the role of dopamine receptors in the nucleus accumbens.
    • 174
    Effects of acamprosate on ethanol-seeking and self-administration in the rat.
    • 88
    Microinjections of dopamine agonists in the nucleus accumbens increase ethanol-reinforced responding
    • 89
    Ventral tegmental microinjections of quinpirole decrease ethanol and sucrose-reinforced responding.
    • 85