Effects of quazepam as a preoperative night hypnotic: comparison with brotizolam

@article{Nishiyama2006EffectsOQ,
  title={Effects of quazepam as a preoperative night hypnotic: comparison with brotizolam},
  author={Tomoki Nishiyama and Koichi Yamashita and Takeshi Yokoyama and Akinobu Imoto and Masanobu Manabe},
  journal={Journal of Anesthesia},
  year={2006},
  volume={21},
  pages={7-12}
}
PurposeThe purpose of this study was to evaluate the effects of quazepam, a long-acting hypnotic, as a preoperative night medication in comparison with brotizolam, a shortacting hypnotic.MethodsTwo hundred patients (aged 30 to 70 years) admitted for elective general anesthesia at various hospitals were enrolled. Quazepam 15 mg, 30 mg, or 45 mg, or brotizolam 0.25 mg (40 patients each), was administered orally at 9 p.m. in the evening of the day before surgery. The control group (40 patients… 

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