Effects of pyridoxine and magnesium on autistic symptoms—Initial observations

@article{Lelord1981EffectsOP,
  title={Effects of pyridoxine and magnesium on autistic symptoms—Initial observations},
  author={Gilbert Lelord and J. P. Muh and C. Barth{\'e}l{\'e}my and J{\"o}elle Martineau and Bernard Garreau and Enoch Callaway},
  journal={Journal of Autism and Developmental Disorders},
  year={1981},
  volume={11},
  pages={219-230}
}
In an open trial, a heterogeneous group of 44 children with autistic symptoms were treated with large doses of vitamin B6 and magnesium. Clinical improvement with worsening on termination of the trial was observed in 15 children. Thirteen responders and 8 nonresponders were retested in a 2-week, crossover, double-blind trial, and the responses to the open trial were confirmed. 
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