Effects of pulsatile glucose stimuli on long-term insulin secretory patterns in islets of Langerhans microdissected from Syrian hamsters.

@article{Souza1993EffectsOP,
  title={Effects of pulsatile glucose stimuli on long-term insulin secretory patterns in islets of Langerhans microdissected from Syrian hamsters.},
  author={Cristina de Souza and P A Rutledge and Albert H. Meier and Illani Atwater},
  journal={Pancreas},
  year={1993},
  volume={8 6},
  pages={726-31}
}
The long-term effects of continuous and pulsatile glucose stimulation of islets of Langerhans microdissected from Syrian hamsters were examined. In the presence of a continuous glucose stimulus insulin secretion peaked during the first 3 h of stimulation followed by a decrease. In the presence of 11.2 mM glucose a second smaller peak of insulin secretion… CONTINUE READING