Effects of puerarin on scopolamine-, mecamylamine-, p-chloroamphetamine- and dizocilpine-induced inhibitory avoidance performance impairment in rats.

@article{Hsieh2002EffectsOP,
  title={Effects of puerarin on scopolamine-, mecamylamine-, p-chloroamphetamine- and dizocilpine-induced inhibitory avoidance performance impairment in rats.},
  author={M Hsieh and Li-Hsuan Kuo and Fan-Hsiu Tsai and Wen-Hsin Wang and Chi-Rei Wu},
  journal={Planta medica},
  year={2002},
  volume={68 10},
  pages={901-5}
}
Puerarin at 10-50 mg/kg attenuated the mecamylamine- but not scopolamine-induced acquisition impairment of inhibitory avoidance performance in an inverse U-shape manner. p-Chloroamphetamine- and dizocilpine-induced acquisition impairment were reversed by puerarin at 25-50 mg/kg. Both piracetam, and tacrine attenuated impairment of inhibitory avoidance… CONTINUE READING