Effects of prolonged ethanol feeding on methionine metabolism in rat liver.

@article{Barak1987EffectsOP,
  title={Effects of prolonged ethanol feeding on methionine metabolism in rat liver.},
  author={Anthony J. Barak and Harriet C Beckenhauer and Dean J. Tuma and S Badakhsh},
  journal={Biochemistry and cell biology = Biochimie et biologie cellulaire},
  year={1987},
  volume={65 3},
  pages={230-3}
}
Pairs of rats were fed control and alcohol liquid diets for periods of 1, 2, 3, and 4 months. The animals were then killed, and their livers analyzed for betaine, S-adenosylmethionine (SAM), methionine synthetase activity, and betaine--homocysteine methyltransferase (BHMT) activity. The results of this time-course study showed that chronic ethanol feeding inhibited the activity of the methionine synthetase throughout the study, but increased the activity of BHMT and lowered betaine levels… CONTINUE READING

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