Effects of prolonged cyanide and thiocyanate feeding in rats.

@article{Philbrick1979EffectsOP,
  title={Effects of prolonged cyanide and thiocyanate feeding in rats.},
  author={Diana J. Philbrick and John B. Hopkins and David C. Hill and J. Craig Alexander and Richard G. Thomson},
  journal={Journal of toxicology and environmental health},
  year={1979},
  volume={5 4},
  pages={
          579-92
        }
}
Male weaning rats were fed a semipurified diet containing 10% casein; this diet restricted in methionine, vitamin B12, and iodine; or the complete and restricted diets supplemented with either 1500 ppm potassium cyanide or 2240 ppm potassium thiocyanate for 11.5 mo. There were no deaths or clinical signs of toxicity. Cyanide, but not thiocyanate, caused a consistent reduction in weight gain in the complete and restricted groups. Both cyanide and thiocyanate caused decreased thyroid gland… CONTINUE READING

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