Effects of prolactin-releasing peptide on tuberoinfundibular dopaminergic neuronal activity and prolactin secretion in estrogen-treated female rats.

@article{Yuan2002EffectsOP,
  title={Effects of prolactin-releasing peptide on tuberoinfundibular dopaminergic neuronal activity and prolactin secretion in estrogen-treated female rats.},
  author={Zung Fan Yuan and Shu-Chuan Yang and Jenn-Tser Pan},
  journal={Journal of biomedical science},
  year={2002},
  volume={9 2},
  pages={112-8}
}
  • Zung Fan Yuan, Shu-Chuan Yang, Jenn-Tser Pan
  • Published 2002 in Journal of biomedical science
Both systemic and central effects of a newly discovered prolactin (PRL)-releasing factor (PRF), prolactin-releasing peptide (PrRP), were determined in this study. Systemic injection of PrRP (1 and 10 microg/rat, i.v.) stimulated PRL secretion in ovariectomized, estrogen-treated rats similar to the effect of another PRF, thyrotropin-releasing hormone (TRH). Pretreatment with a dopamine D2 receptor antagonist, sulpiride (1 microg/rat, i.v.), potentiated the stimulatory effect of both PrRP and TRH… CONTINUE READING