Effects of prior feeding on pharmacokinetics and estimated bioavailability after oral administration of a single dose of microencapsulated erythromycin base in healthy foals.

@article{Lakritz2000EffectsOP,
  title={Effects of prior feeding on pharmacokinetics and estimated bioavailability after oral administration of a single dose of microencapsulated erythromycin base in healthy foals.},
  author={Jeffrey Lakritz and Warren D Wilson and Antoinette E. Marsh and Judy E Mihalyi},
  journal={American journal of veterinary research},
  year={2000},
  volume={61 9},
  pages={1011-5}
}
OBJECTIVE To determine effects of prior feeding on pharmacokinetics and estimated bioavailability of orally administered microencapsulated erythromycin base (MEB) in healthy foals. ANIMALS 6 healthy foals, 3 to 5 months old. PROCEDURE Foals were given 2 doses of MEB (25 mg/kg of body weight, PO). One dose was administered after food was withheld overnight, and the other was administered after foals had consumed hay. The study used a crossover design with a 2-week period between doses. Blood… CONTINUE READING

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