Effects of previous repeated bleedings on the response of plasma epinephrine and norepinephrine levels of conscious dogs in hemorrhagic shock.

A study was conducted on the effects of repeated hemorrhages and reinfusions on the sympathoadrenal response to subsequent hemorrhagic shock. Conscious dogs with carotid and jugular venous cannulae were subjected to hypovolemia of progressively increasing duration for three days. Plasma catecholamines were measured radioenzymatically. Prehemorrhaged animals… (More)