Effects of pretreatment with 2,3,7,8-tetrachlorodibenzofuran on microsomal monooxygenase activity in Drosophila melanogaster.


The effects of tetrachlorodibenzofuran pretreatment was studied in microsomes from adult Drosophila of the Karsnäs 60w strain. Pretreatment for 18 h with 0.2 or 1 mg TCDBF did not increase benzo[alpha]pyrene monooxygenase activity, 7-ethyoxyresorufin deethylase activity or the formation of 2-, 3- or 4-hydroxylated metabolites from biphenyl, in accordance… (More)


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