Effects of pretreatment with magnesium on muscle relaxation and cardiovascular responses in tracheal intubation using the priming principle for vecuronium

@article{Nishiyama2006EffectsOP,
  title={Effects of pretreatment with magnesium on muscle relaxation and cardiovascular responses in tracheal intubation using the priming principle for vecuronium},
  author={M. Nishiyama and Y. Yanbe},
  journal={Journal of Anesthesia},
  year={2006},
  volume={11},
  pages={18-21}
}
In addition to its direct effects on blood vessels, the myocardium, and neuromuscular junctions, magnesium can act as an adrenergic antagonist and can inhibit the release of catecholamines both from adrenergic nerve terminals and from the adrenal medulla. This study was undertaken to evaluate these effects of magnesium on muscle relaxation and cardiovascular response during tracheal intubation. Forty ASA I or II patients undergoing elective surgery were allocated to a magnesium or a control… Expand
1 Citations
Comparative Study of Attenuation of Cardiovascular Responses to Laryngoscopy and Intubation, Employing MgSO4 Vs Normal Saline-A Randomized Double Blinded Study
How to cite this article: Kiran Kumar H, Vijaya Kumar Ta. Comparative study of attenuation of cardiovascular responses to laryngoscopy and intubation, employing MgSO4 vs normal saline a randomizedExpand

References

SHOWING 1-10 OF 36 REFERENCES
Interactions of adrenaline and magnesium on the cardiovascular system of the baboon.
TLDR
It is concluded that Mg has powerful antiarrhythmic effects in the presence of catecholamines and, in addition, may have useful alpha-adrenergic antagonist effects. Expand
Priming of pancuronium with magnesium.
TLDR
It is concluded that pretreatment with magnesium does not usefully increase the speed of onset of action of pancuronium. Expand
Refining the Priming Principle for Vecuronium during Rapid‐sequence Induction of Anesthesia
TLDR
The authors conclude that when vecuronium is used for rapid establishment of neuromuscular blockade during induction of anesthesia, 0.01 mg/ kg iv should be given 4 min prior to 0.1 mg/kg iv. Expand
Rapid Tracheal Intubation with Vecuronium: The Priming Principle
Following the administration of a single 0.1 mg/kg dose of vecuronium bromide, satisfactory conditions for tracheal intubation developed in 156 ± 12 s (mean ± SEM), and the clinical duration of theExpand
Succinylcholine Pretreatment with Magnesium Sulfate
The effect of pretreatment with 60 mg/kg magnesium sulfate on the neuromuscular blockade and consequent potassium release produced by 1.5 mg/kg succinylcholine in ten normal patients was comparedExpand
Succinylcholine Pretreatment with Magnesium Sulfate
: The effect of pretreatment with 60 mg/kg magnesium sulfate on the neuromuscular blockade and consequent potassium release produced by 1.5 mg/kg succinylcholine in ten normal patients was comparedExpand
Is the Priming Principle Both Effective and Safe?
TLDR
It is concluded that priming shortens the onset of NMB similarly between V, P and A but the priming dose producing the most rapid onset ofNMB also results in a high incidence of side effects and therefore thePriming principle should be used with caution. Expand
Clinical intervention studies on magnesium in myocardial infarction.
TLDR
Immediately instituted intravenous Mg treatment should be adopted as part of the routine treatment for patients presenting with AMI, and the mechanisms behind this beneficial effect of the Mg infusions are extensively discussed in this paper. Expand
Clinical intervention studies on magnesium in myocardial infarction.
TLDR
Immediately instituted intravenous Mg treatment should be adopted as part of the routine treatment for patients presenting with AMI, and the mechanisms behind this beneficial effect of the Mg infusions are extensively discussed in this paper. Expand
Pharmacodynamics, Pharmacokinetics, and Intubation Conditions After Priming with Three Different Doses of Vecuronium
TLDR
In conclusion, a priming dose of 10 microgram/kg followed by a 50-micro gram/kg intubating dose 4 min later provides good intubation conditions within 1-2 min, and larger priming doses are not advantageous because they result in higher plasma levels and do not hasten onset time more than the smaller dose. Expand
...
1
2
3
4
...