Effects of preoptic area lesions on muramyl dipeptide-induced sleep and fever

@article{Shoham1989EffectsOP,
  title={Effects of preoptic area lesions on muramyl dipeptide-induced sleep and fever},
  author={Shai Shoham and Clark M. Blatteis and James Krueger},
  journal={Brain Research},
  year={1989},
  volume={476},
  pages={396-399}
}
Lesions of the preoptic area of rabbits caused hyperthermia, although they did not alter sleep-coupled changes in brain temperature, and reduced slow-wave sleep, rapid eye movement sleep, and amplitudes of electroencephalographic slow waves during slow wave sleep. The direction and magnitude of the muramyl dipeptide-induced responses were similar before and after the lesions, although the baseline values upon which the changes were superimposed had shifted. 
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