Effects of postnatal thyroxine administration on brain development, response to postnatal androgen and thyroid regulation in female rats.

@article{Phelps1976EffectsOP,
  title={Effects of postnatal thyroxine administration on brain development, response to postnatal androgen and thyroid regulation in female rats.},
  author={Christopher P. Phelps and J H Leathem},
  journal={The Journal of endocrinology},
  year={1976},
  volume={69 2},
  pages={175-82}
}
Some developmental and functional manifestations of thyroxine (T4) administered on the first 2 days of postnatal life were studied in the female rat. Brain myelinogenesis estimated by brain esterified cholesterol concentration, and brain myelin age estimated by brain total cholesterol concentration, were subsequently determined. Thyroxine treatment resulted in a greater concentration of esterified cholesterol in the brain that saline treatment, but the latter appeared to delay the normal… CONTINUE READING

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