Effects of postnatal ethanol exposure at different developmental phases on neurotrophic factors and phosphorylated proteins on signal transductions in rat brain.

@article{Tsuji2008EffectsOP,
  title={Effects of postnatal ethanol exposure at different developmental phases on neurotrophic factors and phosphorylated proteins on signal transductions in rat brain.},
  author={Ryozo Tsuji and Vittorio Fattori and Shin-Ichi Abe and Lucio Guido Costa and Kumiko Kobayashi},
  journal={Neurotoxicology and teratology},
  year={2008},
  volume={30 3},
  pages={228-36}
}
Exposure to ethanol during development induces severe brain damage resulting in a number of CNS dysfunctions including microencephaly and mental retardation in humans and in laboratory animals. The most vulnerable period to ethanol neurotoxicity coincides with the peak of brain growth spurt. Recently, neurotrophic factors and/or their signal transduction pathways have been reported as a potential relevant target for the developmental neurotoxicity of ethanol. The present studies were designed… CONTINUE READING

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