Effects of positive pressure in odontogenic keratocysts.

  title={Effects of positive pressure in odontogenic keratocysts.},
  author={Shunichi Oka and Yasutaka Kubota and Takashi Yamashiro and Sachie Ogata and Tomohiro Ninomiya and Shuhei Ito and Kanemitsu Shirasuna},
  journal={Journal of dental research},
  volume={84 10},
Intracystic fluid pressure is thought to be involved in odontogenic cyst growth. In this study, we investigated the effects of positive pressure on the expression of interleukin-1alpha (IL-1alpha), matrix metalloproteinases (MMPs), and prostaglandin E2 (PGE2) in odontogenic keratocysts to determine whether this pressure stimulates inflammatory cytokine production and signaling of osteoclastogenic events. Positive pressure enhanced the expression of IL-1alpha mRNA and protein in odontogenic… CONTINUE READING


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