Effects of portacaval shunting on hyperdynamic circulation in bile duct-ligated cirrhotic rats.

@article{Wong1997EffectsOP,
  title={Effects of portacaval shunting on hyperdynamic circulation in bile duct-ligated cirrhotic rats.},
  author={John Tai Hung Wong and Yu-jian Zhang and Samuel Sangkon Lee},
  journal={Journal of hepatology},
  year={1997},
  volume={26 2},
  pages={369-75}
}
BACKGROUND/AIMS Liver cirrhosis and portal hypertension are associated with hyperdynamic circulation. Portacaval shunts are widely used to prevent recurrent hemorrhage, but the hemodynamic effects caused by these procedures have not been well characterized in cirrhosis. We therefore compared the hemodynamic effects of both end-to-side and side-to-side portacaval shunts in normal and cirrhotic rats. METHODS Sprague-Dawley rats were divided into six groups according to the operations they… CONTINUE READING