Effects of polymer and surfactant on the dissolution and transformation profiles of cocrystals in aqueous media

@article{Alhalaweh2014EffectsOP,
  title={Effects of polymer and surfactant on the dissolution and transformation profiles of cocrystals in aqueous media},
  author={Amjad Alhalaweh and Hassan Refat H. Ali and Sitaram Velaga},
  journal={Crystal Growth \& Design},
  year={2014},
  volume={14},
  pages={643-648}
}
Capturing solubility advantages of cocrystals is of great interest, and thus to understand the mechanism by which different excipients could maintain the supersaturation generated by cocrystals at the course of absorption in aqueous media is essential. To achieve this aim, the impact of different excipients on dissolution behavior of indomethacin–saccharin (IND–SAC) were monitored by measuring the concentrations of cocrystal components in the absence and presence of various concentration of… 
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References

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TLDR
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TLDR
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TLDR
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TLDR
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Pharmaceutical cocrystals are of great interest because of their potential to enhance solubility and bioavailability of poorly water-soluble drugs. Cocrystal development is however limited by their…
Formulation of a danazol cocrystal with controlled supersaturation plays an essential role in improving bioavailability.
TLDR
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