Effects of platelet-activating factor and thromboxane A2 on isolated perfused guinea pig liver.

Abstract

Lipid mediators, thromboxane A2 (TxA2) and platelet-activating factor (PAF), are potent vasoconstrictors, and have been implicated as mediators of liver diseases, such as ischemic-reperfusion injury. We determined the effects of a TxA2 analogue (U-46619) and PAF on the vascular resistance distribution and liver weight (wt) in isolated guinea pig livers… (More)

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Cite this paper

@article{Ruan2004EffectsOP, title={Effects of platelet-activating factor and thromboxane A2 on isolated perfused guinea pig liver.}, author={Zonghai Ruan and Toshishige Shibamoto and Tomohiro Shimo and Tomonobu Koizumi and Hideaki Tsuchida and Yasutaka Kurata and Toshitsugu Ogura and Keishi Kubo}, journal={Prostaglandins & other lipid mediators}, year={2004}, volume={73 1-2}, pages={73-85} }