Effects of plant extract neferine on cyclic adenosine monophosphate and cyclic guanosine monophosphate levels in rabbit corpus cavernosum in vitro.

@article{Chen2008EffectsOP,
  title={Effects of plant extract neferine on cyclic adenosine monophosphate and cyclic guanosine monophosphate levels in rabbit corpus cavernosum in vitro.},
  author={Jun Chen and Ji-hong Liu and Tao Wang and Heng-jun Xiao and Chun-ping Yin and Jun Yang},
  journal={Asian journal of andrology},
  year={2008},
  volume={10 2},
  pages={
          307-12
        }
}
AIM To further investigate the relaxation mechanism of neferine (Nef), a bis-benzylisoquinoline alkaloid extracted (isolated) from the green seed embryo of Nelumbo nucifera Gaertn in China, on rabbit corpus cavernosum tissue in vitro. METHODS The effects of Nef on the concentrations of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) in isolated and incubated rabbit corpus cavernosum tissue were recorded using 125I radioimmunoassay. RESULTS The basal… CONTINUE READING

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