Effects of placental insufficiency on the ovine fetal renin-angiotensin system.

@article{Zhang2000EffectsOP,
  title={Effects of placental insufficiency on the ovine fetal renin-angiotensin system.},
  author={Dian Yin Zhang and Eugenie R Lumbers and Giuseppe Simonetta and Jason J. Wu and Julie A Owens and Jeffrey S Robinson and I Caroline Mcmillen},
  journal={Experimental physiology},
  year={2000},
  volume={85 1},
  pages={79-84}
}
We postulated that chronic placental insufficiency would be associated with reduced expression of renal renin and angiotensinogen genes in the fetal sheep. Placental development was restricted in ewes by removing the majority of caruncles prior to mating (placentally restricted (PR) group). The weights of PR fetuses were significantly reduced (P < 0.05, 2.98 +/- 0.33 kg) compared to control fetuses (4.20 +/- 0.30 kg). Kidney weights were also significantly reduced in the PR fetuses (P < 0.05, 8… CONTINUE READING

From This Paper

Topics from this paper.
13 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…