Effects of pituitary adenylate cyclase activating polypeptide in a rat model of traumatic brain injury.

@article{Farkas2004EffectsOP,
  title={Effects of pituitary adenylate cyclase activating polypeptide in a rat model of traumatic brain injury.},
  author={Orsolya Farkas and Andrea Tamas and Andrea Zsombok and Dora Reglodi and J{\'o}zsef P{\'a}l and Andr{\'a}s B{\"u}ki and Istv{\'a}n Lengv{\'a}ri and John Theodore Povlishock and Tam{\'a}s D{\'o}czi},
  journal={Regulatory peptides},
  year={2004},
  volume={123 1-3},
  pages={69-75}
}
Pituitary adenylate cyclase activating polypeptide (PACAP) is a widely distributed neuropeptide that has numerous different actions. Recent studies have shown that PACAP exerts neuroprotective effects not only in vitro but also in vivo, in animal models of global and focal cerebral ischemia, Parkinson's disease and axonal injuries. Traumatic brain injury has an increasing mortality and morbidity and it evokes diffuse axonal injury which further contributes to its damaging effects. The aim of… CONTINUE READING

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