Effects of pitavastatin on the expression of VCAM-1 and its target gene miR-126 in cultured human umbilical vein endothelial cells.

@article{Xu2014EffectsOP,
  title={Effects of pitavastatin on the expression of VCAM-1 and its target gene miR-126 in cultured human umbilical vein endothelial cells.},
  author={Qinglu Xu and Tianzhu Luan and Songbin Fu and Jian Yang and Chao Jiang and Fangfang Xia},
  journal={Cardiovascular therapeutics},
  year={2014},
  volume={32 5},
  pages={193-7}
}
OBJECTIVES Reducing the expression of endothelial cell adhesion molecules is conducive to the decrease of inflammation-induced vascular complications. In this study, we observed pitavastatin on expression of vascular cell adhesion molecule-1 (VCAM-1) and its influence on VCAM-1's target gene miR-126 in endothelial cells. The purpose of this study is to explore the mechanism of pitavastatin in prevention and treatment of atherosclerosis. METHODS HUVEC were cultured in M1640 and passages 2-5… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 3 times. VIEW TWEETS