Effects of physiological increments in renal arterial plasma osmolality on renin secretion rate.

@article{Kopp1983EffectsOP,
  title={Effects of physiological increments in renal arterial plasma osmolality on renin secretion rate.},
  author={Ulla C. Kopp and Gerald F. Dibona},
  journal={The Journal of laboratory and clinical medicine},
  year={1983},
  volume={102 2},
  pages={
          250-9
        }
}
The present study was performed in anesthetized dogs to examine the effects of physiological increments in renal arterial plasma osmolality on basal renin secretion rate and on the response of renin secretion rate to RNS. Three concentrations of hypertonic NaCl were infused into the renal artery (i.r.a.) at 0.38 ml/min for 3 min; i.r.a. Hypertonic NaCl at 0.45M, 0.9M, and 1.8M increased the renal arterial plasma osmolality by 6 +/- 2, 8 +/- 2, and 28 +/- 9 mOsm/kg H2O, respectively. NaCl, 0.45M… CONTINUE READING

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