Effects of phthalate esters on the sensitization phase of contact hypersensitivity induced by fluorescein isothiocyanate.

@article{Imai2006EffectsOP,
  title={Effects of phthalate esters on the sensitization phase of contact hypersensitivity induced by fluorescein isothiocyanate.},
  author={Yasuyuki Imai and Ayumi Kondo and Hiromi Iizuka and Takashi Maruyama and Kohta Kurohane},
  journal={Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology},
  year={2006},
  volume={36 11},
  pages={1462-8}
}
BACKGROUND Many different types of phthalate ester are used as plasticizers and are thus found in the air. There have been several studies that suggest an association between allergies and phthalate esters. We previously found that di-butyl phthalate (DBP) has an adjuvant effect in a mouse contact hypersensitivity model, in which fluorescein isothiocyanate (FITC) is involved as an immunogenic hapten. OBJECTIVE We examined whether other phthalate esters enhance the process of sensitization to… CONTINUE READING

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