Effects of photobiomodulation combined with MSCs transplantation on the repair of spinal cord injury in rat

@article{Chen2020EffectsOP,
  title={Effects of photobiomodulation combined with MSCs transplantation on the repair of spinal cord injury in rat},
  author={Hongli Chen and Yunhao Wang and Wenjun Tu and H. Wang and H. Yin and H. Sha and Yingxin Li},
  journal={Journal of Cellular Physiology},
  year={2020},
  volume={236},
  pages={921 - 930}
}
Stem cell transplantation has shown promising regenerative effects against neural injury, and photobiomodulation (PBM) can aid tissue recovery. This study aims to evaluate the therapeutic effect of human umbilical cord mesenchymal stem cells (hUCMSCs) and laser alone or combined on spinal cord injury (SCI). The animals were divided into SCI, hUCMSCs, laser treatment (LASER) and combination treatment (hUCMSCs + LASER) groups. Cell‐enriched grafts of hUCMSCs (1 × 106 cells/ml) were injected at… Expand
Combined Effects of Low Level Laser Therapy and Inducers on the Neural Differentiation of Mesenchymal Stem Cells
Low level laser therapy (LLLT) improves the therapeutic effectiveness of stem cell therapy for neurological injury through its ability to enhance stem differentiation and protect against neuronalExpand
The effect of low-level laser therapy on pathophysiology and locomotor recovery after traumatic spinal cord injuries: a systematic review and meta-analysis
TLDR
The results showed that regardless of laser type, laser beams with a wavelength between 600 and 850 nm significantly suppress inflammation and led inflammatory cells to M2 polarization and wound healing and the LLLT showed promising potential to modulate pathophysiological events and recovery after TSCI. Expand

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