Effects of phosphoramidon, BQ 788, and BQ 123 on coronary and cardiac dysfunctions of the failing hamster heart.

@article{Fontaine1998EffectsOP,
  title={Effects of phosphoramidon, BQ 788, and BQ 123 on coronary and cardiac dysfunctions of the failing hamster heart.},
  author={Emeline Fontaine and Stephanie Viau and Ga{\"e}tan Jasmin and Louis Dumont},
  journal={Journal of cardiovascular pharmacology},
  year={1998},
  volume={32 1},
  pages={12-20}
}
Coronary dysfunctions identified in the presence of chronic heart failure are an important pathophysiologic abnormality that influences the prognosis of the disease. Because the endothelin pathway plays a significant role in the increased peripheral vascular tone associated with heart failure, we hypothesized that the endothelin pathway may be involved in the abnormal coronary vasomotion associated with this pathologic condition. Experiments were carried out in failing hearts (UM-X7.1… CONTINUE READING

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