Effects of pertussis toxin on signal transductions via P2-purinergic receptors in A-431 human epidermoidal carcinoma cells.

@article{Sugita1994EffectsOP,
  title={Effects of pertussis toxin on signal transductions via P2-purinergic receptors in A-431 human epidermoidal carcinoma cells.},
  author={Kyoichi Sugita and Kinji Kurihara and Kazuo Hosoi and Toshiko Atsumi and Toshihiro Takahashi and Masayuki Kohno and Takao Ueha},
  journal={Enzyme & protein},
  year={1994},
  volume={48 4},
  pages={222-8}
}
In A-431 cells, stimulation of P2-purinergic receptors with extracellular ATP caused production of inositol 1,4,5-trisphosphate (InsP3), followed by mobilization of Ca2+ from intracellular stores; Ca2+ influx from the extracellular fluid and breakdown of phosphatidylcholine (PtdCho) also accompanied this InsP3/Ca2+ signalling. When A-431 cells were… CONTINUE READING