Effects of peroxisome proliferator-activated receptor gamma and its ligand on blood-retinal barrier in a streptozotocin-induced diabetic model.

Abstract

PURPOSE To clarify whether endogenous peroxisome proliferator-activated receptor gamma (PPARgamma) and its ligand, rosiglitazone, affect retinal leukostasis and the associated vascular leakage using an experimental diabetic model. METHODS Diabetes was induced in heterozygous PPARgamma+/- mice and Brown Norway rats with an intraperitoneal streptozotocin… (More)

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@article{Muranaka2006EffectsOP, title={Effects of peroxisome proliferator-activated receptor gamma and its ligand on blood-retinal barrier in a streptozotocin-induced diabetic model.}, author={Kimimasa Muranaka and Yasuo Yanagi and Yasuhiro Tamaki and Tomohiko Usui and Naoto Kubota and Aya Iriyama and Yasuo Terauchi and Takashi Kadowaki and Makoto Araie}, journal={Investigative ophthalmology & visual science}, year={2006}, volume={47 10}, pages={4547-52} }