Effects of peripheral CCK receptor blockade on feeding responses to duodenal nutrient infusions in rats.

@article{Reidelberger2003EffectsOP,
  title={Effects of peripheral CCK receptor blockade on feeding responses to duodenal nutrient infusions in rats.},
  author={R. Reidelberger and Dean G. Heimann and L. Kelsey and M. Hulce},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2003},
  volume={284 2},
  pages={
          R389-98
        }
}
  • R. Reidelberger, Dean G. Heimann, +1 author M. Hulce
  • Published 2003
  • Biology, Medicine
  • American journal of physiology. Regulatory, integrative and comparative physiology
  • Type A cholecystokinin receptor (CCKAR) antagonists differing in blood-brain barrier permeability were used to test the hypothesis that duodenal delivery of protein, carbohydrate, and fat produces satiety in part by an essential CCK action at CCKARs located peripheral to the blood-brain barrier. Fasted rats with open gastric fistulas received devazepide (1 mg/kg iv) or A-70104 (700 nmol. kg(-1). h(-1) iv) and either a 30-min intravenous infusion of CCK-8 (10 nmol. kg(-1). h(-1)) or duodenal… CONTINUE READING
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    Role of peptide YY(3-36) in the satiety produced by gastric delivery of macronutrients in rats.
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