Effects of peripheral CCK receptor blockade on food intake in rats.

@article{Reidelberger2003EffectsOP,
  title={Effects of peripheral CCK receptor blockade on food intake in rats.},
  author={R. Reidelberger and D. Castellanos and M. Hulce},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2003},
  volume={285 2},
  pages={
          R429-37
        }
}
  • R. Reidelberger, D. Castellanos, M. Hulce
  • Published 2003
  • Chemistry, Medicine
  • American journal of physiology. Regulatory, integrative and comparative physiology
  • Type A cholecystokinin receptor (CCKAR) antagonists differing in blood-brain barrier permeability were used to test the hypothesis that satiety is mediated, in part, by CCK action at CCKARs located peripheral to the blood-brain barrier. At dark onset, non-food-deprived rats received a bolus injection of devazepide (2.5 micromol/kg iv), a 3-h infusion of A-70104 (1 or 3 micromol x kg-1 x h-1 iv), or vehicle either alone or coadministered with a 3-h infusion of CCK-8 (10 nmol x kg-1 x h-1 iv) or… CONTINUE READING
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