Effects of perioperative nesiritide in patients with left ventricular dysfunction undergoing cardiac surgery:the NAPA Trial.

@article{Mentzer2007EffectsOP,
  title={Effects of perioperative nesiritide in patients with left ventricular dysfunction undergoing cardiac surgery:the NAPA Trial.},
  author={Robert M. Mentzer and Mehmet C Oz and Robert N. Sladen and Allen H Graeve and Robert Frederick Hebeler and John M Luber and Nicholas Gerard Smedira},
  journal={Journal of the American College of Cardiology},
  year={2007},
  volume={49 6},
  pages={716-26}
}
OBJECTIVES The purpose of this study was to determine the role nesiritide might play in patients with left ventricular dysfunction undergoing coronary artery bypass grafting (CABG) using cardiopulmonary bypass (CPB). BACKGROUND Given the hemodynamic, neurohormonal, and renal effects of natriuretic peptides, nesiritide might be useful in the management of patients undergoing cardiac surgery. METHODS This prospective, double-blind, exploratory evaluation randomly assigned patients with… CONTINUE READING

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