Effects of perinatal loratadine exposure on male rat reproductive organ development.

@article{McIntyre2003EffectsOP,
  title={Effects of perinatal loratadine exposure on male rat reproductive organ development.},
  author={Barry S McIntyre and Paul M Vancutsem and Kimberley Anne Treinen and Richard E Morrissey},
  journal={Reproductive toxicology},
  year={2003},
  volume={17 6},
  pages={691-7}
}
Normal pre- and postnatal male reproductive development and function is dependent upon testicular androgen production and is sensitive to antiandrogenic perturbations. It was of interest to determine if the H(1) histamine antagonist loratadine had the potential to alter androgen-mediated reproductive development in the rat, a sensitive species for detecting… CONTINUE READING