Effects of perchlorate on the molecules of excitation-contraction coupling of skeletal and cardiac muscle

@article{Ma1993EffectsOP,
  title={Effects of perchlorate on the molecules of excitation-contraction coupling of skeletal and cardiac muscle},
  author={Jianfei Ma and Kevin D Anderson and Roman O Shirokov and R Levis and Adom Gonz{\'a}lez and Miloslav Karhanek and M. Marlene Hosey and Gerhard Meissner and Eduardo R{\'i}os},
  journal={The Journal of General Physiology},
  year={1993},
  volume={102},
  pages={423 - 448}
}
To understand the nature of the transmission process of excitation-contraction (EC) coupling, the effects of the anion perchlorate were investigated on the voltage sensor (dihydropyridine receptor, DHPR) and the Ca release channel (ryanodine receptor, RyR) of the sarcoplasmic reticulum (SR). The molecules, from rabbit skeletal muscle, were either separated in membrane vesicular fractions or biochemically purified so that the normal EC coupling interaction was prevented. Additionally, the effect… CONTINUE READING
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Journal of General Physiology

  • H ET
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Effects of perchiorate on excitation - contraction coupling in frog and crayfish skeletal muscle

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Plasmalemmal resting voltage modulation of caffeinecontractures in mammalian skeletal muscles: effects of dantrolene and perchiorate

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