Effects of pentoxifylline in Adriamycin-induced renal disease in rats

Abstract

Tumor necrosis factor-α (TNF-α) is a mediator of inflammation in human and animal renal disease. Pentoxiphylline (PTX) is an inhibitor of TNF-α. In this study we examined the effects of PTX on TNF-α, proteinuria, nitrite production, and apoptosis in an experimental model of Adriamycin (ADR) nephropathy in rats. Rats were divided into four groups: untreated… (More)
DOI: 10.1007/s00467-004-1538-5

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@article{Usta2004EffectsOP, title={Effects of pentoxifylline in Adriamycin-induced renal disease in rats}, author={Yusuf Hakan Usta and Ugur Burcin Ismailoglu and Aysin S Bakkaloglu and Dicle Orhan and Nesrin Beşbaş and Inçi Sahin-Erdemli and Seza Ozen}, journal={Pediatric Nephrology}, year={2004}, volume={19}, pages={840-843} }