Effects of pentoxifylline administration on urinary N-acetyl-beta-glucosaminidase excretion in type 2 diabetic patients: a short-term, prospective, randomized study.

@article{Navarro2003EffectsOP,
  title={Effects of pentoxifylline administration on urinary N-acetyl-beta-glucosaminidase excretion in type 2 diabetic patients: a short-term, prospective, randomized study.},
  author={Juan F. Navarro and Carmen J Mora and M Jose S{\'a}nchez Muros and Manuel Maca and Javier Garca},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={2003},
  volume={42 2},
  pages={264-70}
}
BACKGROUND Tubulointerstitial injury is a major feature of diabetic nephropathy and an important predictor of renal dysfunction. In 45 patients with type 2 diabetes mellitus (DM), we prospectively analyzed urinary excretion of N-acetyl-beta-glucosaminidase (NAG), a marker of tubular renal damage; the potential relationship with urinary protein excretion; and effects of pentoxifylline (PTF) administration. METHODS Forty-five patients with type 2 DM initially were compared with 15 healthy… CONTINUE READING

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