• DOI:10.1016/0006-2952(83)90232-0
Corpus ID: 29838565

Effects of pentobarbital and veratridine on phosphatidylinositol and phosphatidate metabolism in rat parotid acinar cells.

@article{Miller1983EffectsOP,
  title={Effects of pentobarbital and veratridine on phosphatidylinositol and phosphatidate metabolism in rat parotid acinar cells.},
  author={J. Miller and C. Kowal},
  journal={Biochemical pharmacology},
  year={1983},
  volume={32 14},
  pages={
          2237-41
        }
}

J. Miller, C. Kowal

Published 1983

Chemistry, Medicine

Biochemical pharmacology

The metabolism of phosphatidylinositol and phosphatidate was studied in isolated rat parotid cells, incubated in a physiological buffer containing [32P]phosphate or [3H]glycerol. Carbamylcholine and epinephrine stimulated 32P incorporation into both of these phospholipids, causing their half-maximal effects at 2 and 0.8 microM respectively. The former concentration is much lower than that anticipated from binding studies. The Hill coefficients for carbamylcholine activation of 32P incorporation… CONTINUE READING

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