Effects of parenteral arginine supplementation on the intestinal adaptive response after massive small bowel resection in the rat.

@article{Welters1999EffectsOP,
  title={Effects of parenteral arginine supplementation on the intestinal adaptive response after massive small bowel resection in the rat.},
  author={Carlo F M Welters and Cornelis H. C. Dejong and Nicolaas E.P. Deutz and Erik Heineman},
  journal={The Journal of surgical research},
  year={1999},
  volume={85 2},
  pages={259-66}
}
BACKGROUND Arginine (ARG) and its metabolic products (polyamines and nitric oxide) are known to affect gut function and protein synthesis in various tissues. The aim was to study the effect of parenteral ARG supplementation on intestinal adaptation and intestinal function in rats after massive small bowel resection (SBR). METHODS Fasted rats (275 g) were studied 24 h after 80% SBR. At t = 6 h, t = 12 h, and t = 18 h after SBR, a 300 mM ARG solution (ARG, n = 9), 5 ml/100 g body weight, was… CONTINUE READING
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