Effects of pamidronate on human alveolar osteoblasts in vitro.


PURPOSE Administration of bisphosphonates has recently been associated with the development of osteonecrotic lesions of the jaw (ONJ). To elucidate the potential contributions of osteogenic cells to the development and regeneration of ONJ, we have isolated primary cells from human alveolar and long/iliac bones, and examined the effects of pamidronate on… (More)
DOI: 10.1016/j.joms.2011.05.002

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