Effects of paclitaxel nanocrystals surface charge on cell internalization.

Abstract

In this study, we investigated the influence of paclitaxel nanocrystals (PTX-NC) surface charge on cell internalization and cell cytotoxicity. PTX-NCs were prepared using the nano-precipitation method. The surface-modified PTX-NCs were prepared using an absorption method with positively charged poly(allylamine hydrochloride) (PAH) and negatively charged… (More)
DOI: 10.1016/j.ejps.2016.08.014

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