Effects of pH and cholesterol on DMPA membranes: a solid state 2H- and 31P-NMR study.

@article{Pott1995EffectsOP,
  title={Effects of pH and cholesterol on DMPA membranes: a solid state 2H- and 31P-NMR study.},
  author={Tanja Pott and J C Maillet and Erick J. Dufourc},
  journal={Biophysical journal},
  year={1995},
  volume={69 5},
  pages={1897-908}
}
The effect of pH and cholesterol on the dimyristoylphosphatidic acid (DMPA) model membrane system has been investigated by solid state 2H- and 31P-NMR. It has been shown that each of the three protonation states of the DMPA molecule corresponds to a 31P-NMR powder pattern with characteristic delta sigma values; this implies additionally that the proton exchange on the membrane surface is slow on the NMR time scale (millisecond range). Under these conditions, the 2H-labeled lipid chains sense… CONTINUE READING