Effects of p38 MAPK signaling pathway on the odontoblastic differentiation of human dental pulp cells

@inproceedings{Wenxi2013EffectsOP,
  title={Effects of p38 MAPK signaling pathway on the odontoblastic differentiation of human dental pulp cells},
  author={He Wen-xi},
  year={2013}
}
AIM:To investigate the effects of p38 mitogen-activated protein kinase(MAPK) signaling pathway on the odontoblastic differentiation of human dental pulp cells(hDPCs).METHODS:Tissue block enzymolytic method was used to isolate and culture hDPCs.hDPCs of Passage 3 was cultured with mineralization inducing medium containing 20 μmol/L SB203580,a p38 MAPK inhibitor.Cells cultured without SB203580 served as the controls.7 days after induction,quantitative real-time RT-PCR was conducted to detect the… CONTINUE READING