Effects of p-Synephrine alone and in Combination with Selected Bioflavonoids on Resting Metabolism, Blood Pressure, Heart Rate and Self-Reported Mood Changes

@article{Stohs2011EffectsOP,
  title={Effects of p-Synephrine alone and in Combination with Selected Bioflavonoids on Resting Metabolism, Blood Pressure, Heart Rate and Self-Reported Mood Changes},
  author={S. Stohs and H. Preuss and S. C. Keith and P. L. Keith and Howard Miller and G. Kaats},
  journal={International Journal of Medical Sciences},
  year={2011},
  volume={8},
  pages={295 - 301}
}
Bitter orange (Citrus aurantium) extract is widely used in dietary supplements for weight management and sports performance. Its primary protoalkaloid is p-synephrine. Most studies involving bitter orange extract and p-synephrine have used products with multiple ingredients. The current study assessed the thermogenic effects of p-synephrine alone and in conjunction with the flavonoids naringin and hesperidin in a double-blinded, randomized, placebo-controlled protocol with 10 subjects per… Expand

Paper Mentions

Interventional Clinical Trial
The purpose of this study is to determine whether subjects taking a supplement designed to increase metabolic rate will have a positive effect on body composition (fat mass, muscle… Expand
ConditionsWeight Loss
InterventionDietary Supplement, Other
Safety evaluation of p‐synephrine following 15 days of oral administration to healthy subjects: A clinical study
A 60day double-blind, placebo-controlled safety study involving Citrus aurantium (bitter orange) extract.
  • G. Kaats, Howard Miller, H. Preuss, S. Stohs
  • Chemistry, Medicine
  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 2013
A Review of the Receptor-Binding Properties of p-Synephrine as Related to Its Pharmacological Effects
Effects of p-Synephrine and Caffeine Ingestion on Substrate Oxidation during Exercise
Acute p-synephrine ingestion increases fat oxidation rate during exercise.
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